Submissions from 2021
Targeting tat–tar rna interaction for hiv-1 inhibition, Awadh Alanazi, Andrey Ivanov, Namita Kumari, Xionghao Lin, Songping Wang, Dmytro Kovalskyy, and Sergei Nekhai
The gut microbiome in sickle cell disease: Characterization and potential implications, Hassan Brim, James Taylor, Muneer Abbas, Kimberly Vilmenay, Mohammad Daremipouran, Sudhir Varma, Edward Lee, Betty Pace, Waogwende L. Song-Naba, Kalpna Gupta, Sergei Nekhai, Patricia O’Neil, and Hassan Ashktorab
Urinary Kringle Domain-Containing Protein HGFL: A Validated Biomarker of Early Sickle Cell Anemia-Associated Kidney Disease, Sergei Nekhai, Xionghao Lin, Simran Soni, Ammanuel Taye, Nathan Smith, Nowah Afangbedji, Santosh L. Saraf, Victor R. Gordeuk, James G. Taylor, and Marina Jerebtsova
Protein Phosphatase 1 Regulates Human Cytomegalovirus Protein Translation by Restraining AMPK Signaling, Carmen Stecher, Sanja Marinkov, Lucia Mayr-Harting, Ana Katic, Marie Theres Kastner, Franz J.J. Rieder-Rommer, Xionghao Lin, Sergei Nekhai, and Christoph Steininger
Submissions from 2020
The CYB5R3c.350C>G and G6PD A alleles modify severity of anemia in malaria and sickle cell disease, Victor R. Gordeuk, Binal N. Shah, Xu Zhang, Philip E. Thuma, Stenford Zulu, Rodgers Moono, N. Scott Reading, Jihyun Song, Yingze Zhang, Mehdi Nouraie, Andrew Campbell, Caterina P. Minniti, Sohail R. Rana, Deepika S. Darbari, Gregory J. Kato, Mei Niu, Oswaldo L. Castro, Roberto Machado, Mark T. Gladwin, and Josef T. Prchal
Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription, Andrey Ivanov, Palaniappan Ramanathan, Christian Parry, Philipp A. Ilinykh, Xionghao Lin, Michael Petukhov, Yuri Obukhov, Tatiana Ammosova, Gaya K. Amarasinghe, Alexander Bukreyev, and Sergei Nekhai
Macrophage HIV-1 gene expression and delay resolution of inflammation in HIV-Tg Mice, Marina Jerebtsova, Asrar Ahmad, Namita Kumari, Ornela Rutagarama, and Sergei Nekhai
HIV-1 transcription inhibitor 1E7-03 restores LPS-induced alteration of lung leukocytes’ infiltration dynamics and resolves inflammation in HIV transgenic mice, Marina Jerebtsova, Asrar Ahmad, Xiaomei Niu, Ornela Rutagarama, and Sergei Nekhai
Association between plasma and urinary orosomucoid and chronic kidney disease in adults with sickle cell disease, Marina Jerebtsova, Ammanuel Taye, Nathan Smith, Nowah Afangbedji, Daniel Stokes, Xiaomei Niu, Sharmin Diaz, James G. Taylor, and Sergei Nekhai
Structural Optimization of 2,3-Dihydro-1H-cyclopenta[ b]quinolines Targeting the Noncatalytic RVxF Site of Protein Phosphatase 1 for HIV-1 Inhibition, Xionghao Lin, Ayyiliath M. Sajith, Songping Wang, Namita Kumari, Meng S. Choy, Asrar Ahmad, Dana R. Cadet, Xinbin Gu, Andrey I. Ivanov, Wolfgang Peti, Amol Kulkarni, and Sergei Nekhai
Depriving Iron Supply to the Virus Represents a Promising Adjuvant Therapeutic Against Viral Survival, Wei Liu, Shuping Zhang, Sergei Nekhai, and Sijin Liu
Tricuspid regurgitation velocity and other biomarkers of mortality in children, adolescents and young adults with sickle cell disease in the United States: The PUSH study, Mehdi Nouraie, Deepika S. Darbari, Sohail Rana, Caterina P. Minniti, Oswaldo L. Castro, Lori Luchtman-Jones, Craig Sable, Niti Dham, Gregory J. Kato, Mark T. Gladwin, Gregory Ensing, Manuel Arteta, Andrew Campbell, James G. Taylor, Sergei Nekhai, and Victor R. Gordeuk
Establishing rules for self-adhesion and aggregation of N-glycan sugars using virus glycan shields, Eric Ogharandukun, Wintana Tewolde, Elbethel Damtae, Songping Wang, Andrey Ivanov, Namita Kumari, Sergei Nekhai, and Preethi L. Chandran
Influence of single parenthood on cardiopulmonary function in pediatric patients with sickle cell anemia, Xu Zhang, Kiarri N. Kershaw, Caterina P. Minniti, Andrew Campbell, Sohail R. Rana, Deepika S. Darbari, Lori Luchtman-Jones, Craig Sable, Niti Dham, Gregory Ensing, Manuel Arteta, James G. Taylor, Lewis L. Hsu, Sergei Nekhai, and Victor R. Gordeuk
S100B has pleiotropic effects on vaso-occlusive manifestations in sickle cell disease, Xu Zhang, Binal N. Shah, Wei Zhang, Santosh L. Saraf, Mehdi Nouraie, Sergei Nekhai, Roberto F. Machado, Mark T. Gladwin, and Victor R. Gordeuk
Peripheral blood mononuclear cells show prominent gene expression by erythroid progenitors in diseases characterized by heightened erythropoiesis, Xu Zhang, Jihyun Song, Binal N. Shah, Sergei Nekhai, Galina Miasnikova, Adelina Sergueeva, Josef T. Prchal, and Victor R. Gordeuk
Submissions from 2019
Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition, Xionghao Lin, Tatiana Ammosova, Meng S. Choy, Colette A. Pietzsch, Andrey Ivanov, Asrar Ahmad, Yasemin Saygideğer, Namita Kumari, Dmytro Kovalskyy, Aykut Üren, Wolfgang Peti, Alexander Bukreyev, and Sergei Nekhai
Chromomycin, an antibiotic produced by Streptomyces flaviscleroticus might play a role in the resistance to oxidative stress and is essential for viability in stationary phase, Divya Prajapati, Namita Kumari, Keyur Dave, Vaidehi Chatupale, and Jayashree Pohnerkar
Submissions from 2018
Protein Phosphatase 1-Targeting Small-Molecule C31 Inhibits Ebola Virus Replication, Tatiana Ammosova, Colette A. Pietzsch, Yasemin Saygideǧer, Andrey Ilatovsky, Xionghao Lin, Andrey Ivanov, Namita Kumari, Marina Jerebtsova, Amol Kulkarni, Michael Petukhov, Aykut Üren, Alexander Bukreyev, and Sergei Nekhai
Protein phosphatase 1α interacts with Venezuelan equine encephalitis virus capsid protein and regulates viral replication through modulation of capsid phosphorylation, Brian D. Carey, Tatiana Ammosova, Chelsea Pinkham, Xionghao Lin, Weidong Zhou, Lance A. Liotta, Sergei Nekhai, and Kylene Kehn-Hall
Establishing a national sickle cell disease program in the Republic of Congo, Alexis Elira Dokekias, Lydie Ngolet, Juan Salomon-Andonie, Sergei Nekhai, and James G. Taylor
HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription, Andrey Ivanov, Xionghao Lin, Tatiana Ammosova, Andrey V. Ilatovskiy, Namita Kumari, Hatajai Lassiter, Nowah Afangbedji, Xiaomei Niu, Michael G. Petukhov, and Sergei Nekhai
Identification of ceruloplasmin as a biomarker of chronic kidney disease in urine of sickle cell disease patients by proteomic analysis, Marina Jerebtsova, Santosh L. Saraf, Xionghao Lin, Gillian Lee, Elena Afia Adjei, Namita Kumari, Nowah Afangbedji, Rasha Raslan, Charlee McLean, Victor R. Gordeuk, and Sergei Nekhai
Urinary orosomucoid is associated with progressive chronic kidney disease stage in patients with sickle cell anemia, Marina Jerebtsova, Santosh L. Saraf, Simran Soni, Nowah Afangbedji, Xionghao Lin, Rasha Raslan, Victor R. Gordeuk, and Sergei Nekhai
RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice, Alfia Khaibullina, Elena A. Adjei, Nowah Afangbedji, Andrey Ivanov, Namita Kumari, Luis E.F. Almeida, Zenaide M.N. Quezado, Sergei Nekhai, and Marina Jerebtsova
Corrigendum: Ebola VP40 in exosomes can cause immune cell dysfunction [Front. Microbiol., 7, (2016), (1765)] doi: 10.3389/fmicb.2016.01765, Michelle L. Pleet, Allison Mathiesen, Catherine DeMarino, Yao A. Akpamagbo, Robert A. Barclay, Angela Schwab, Sergey Iordanskiy, Gavin C. Sampey, Benjamin Lepene, Philipp A. Ilinykh, Alexander Bukreyev, Sergei Nekhai, M. Javad Aman, and Fatah Kashanchi
RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription, Charles Adrien Richard, Vincent Rincheval, Safa Lassoued, Jenna Fix, Christophe Cardone, Camille Esneau, Sergei Nekhai, Marie Galloux, Marie Anne Rameix-Welti, Christina Sizun, and Jean François Eléouët
Phosphorylated VP30 of marburg virus is a repressor of transcription, Bersabeh Tigabu, Palaniappan Ramanathan, Andrey Ivanov, Xionghao Lin, Philipp A. Ilinykh, Christian S. Parry, Alexander N. Freiberg, Sergei Nekhai, and Alexander Bukreyev
Submissions from 2017
Enzymopenic congenital methemoglobinemia in children of the Republic of Sakha (Yakutia), Tatiana E. Burtseva, Tatiana N. Ammosova, Natalia N. Protopopova, Svetlana Y. Yakovleva, and Maya P. Slobodchikova
Central sensitization associated with low fetal hemoglobin levels in adults with sickle cell anemia, Deepika S. Darbari, Kathleen J. Vaughan, Katherine Roskom, Cassie Seamon, Lena Diaw, Meghan Quinn, Anna Conrey, Alan N. Schechter, Jennifer A. Haythornthwaite, Myron A. Waclawiw, Gwenyth R. Wallen, Inna Belfer, and James G. Taylor
Protein phosphatase-1 -targeted small molecules, iron chelators and curcumin analogs as HIV-1 antivirals, Xionghao Lin, Tatyana Ammosova, Namita Kumari, and Sergei Nekhai
Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03, Xionghao Lin, Namita Kumari, Catherine DeMarino, Yasemin Saygideger Kont, Tatiana Ammosova, Amol Kulkarni, Marina Jerebtsova, Guelaguetza Vazquez-Meves, Andrey Ivanov, Dmytro Kovalskyy, Aykut üren, Fatah Kashanchi, and Sergei Nekhai
Prospective study of thrombosis and thrombospondin-1 expression in Chuvash polycythemia, Adelina Sergueeva, Galina Miasnikova, Binal N. Shah, Jihyun Song, Ekaterina Lisina, Daniel J. Okhotin, Mehdi Nouraie, Sergei Nekhai, Tatiana Ammosova, Xiao Mei Niu, Josef T. Prchal, Xu Zhang, and Victor R. Gordeuk
Submissions from 2016
Protein phosphatase-1 regulates expression of neuregulin-1, Tatiana Ammosova, Kareem Washington, Jamie Rotimi, Namita Kumari, Kahli A. Smith, Xiaomei Niu, Marina Jerebtsova, and Sergei Nekhai
Protein Phosphatase-1 regulates Rift Valley fever virus replication, Alan Baer, Nazly Shafagati, Ashwini Benedict, Tatiana Ammosova, Andrey Ivanov, Ramin M. Hakami, Kaori Terasaki, Shinji Makino, Sergei Nekhai, and Kylene Kehn-Hall
Preventing delayed hemolytic transfusion reactions in sickle cell disease, Oswaldo Castro, Patricia Oneal, Adriana Medina, Gladys Onojobi, and Victor R. Gordeuk
Kidney disease among patients with sickle cell disease, hemoglobin SS and SC, Paul Drawz, Sabarish Ayyappan, Mehdi Nouraie, Santosh Saraf, Victor Gordeuk, Thomas Hostetter, Mark T. Gladwin, and Jane Little
Therapeutic potential of the heme oxygenase-1 inducer hemin against Ebola virus infection, Hanxia Huang, Krishnamurthy Konduru, Veronica Solovena, Zhao Hua Zhou, Namita Kumari, Kazuyo Takeda, Sergei Nekhai, Sina Bavari, Gerardo G. Kaplan, Kenneth M. Yamada, and Subhash Dhawan
Ebola VP40 in exosomes can cause immune cell dysfunction, Michelle L. Pleet, Allison Mathiesen, Catherine DeMarino, Yao A. Akpamagbo, Robert A. Barclay, Angela Schwab, Sergey Iordanskiy, Gavin C. Sampey, Benjamin Lepene, Sergei Nekhai, M. J. Aman, and Fatah Kashanchi
Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells, Steven Santos, Yuri Obukhov, Sergei Nekhai, Tatiana Pushkarsky, Beda Brichacek, Michael Bukrinsky, and Sergey Iordanskiy
A genetic variation associated with plasma erythropoietin and a non-coding transcript of PRKAR1A in sickle cell disease, Xu Zhang, Binal N. Shah, Wei Zhang, Santosh L. Saraf, Galina Miasnikova, Adelina Sergueeva, Tatiana Ammosova, Xiaomei Niu, Mehdi Nouraie, Sergei Nekhai, Oswaldo Castro, Mark T. Gladwin, Josef T. Prchal, Joe G.N. Garcia, Roberto F. Machado, and Victor R. Gordeuk
Submissions from 2015
Novel inducers of fetal globin identified through high throughput screening (HTS) are active in vivo in anemic baboons and transgenic mice, Michael S. Boosalis, Jose I. Sangerman, Gary L. White, Roman F. Wolf, Ling Shen, Yan Dai, Emily White, Levi H. Makala, Biaoru Li, Betty S. Pace, Mehdi Nouraie, Douglas V. Faller, and Susan P. Perrine
Dexmedetomidine ameliorates nocifensive behavior in humanized sickle cell mice, Gabriela Calhoun, Li Wang, Luis E.F. Almeida, Nicholas Kenyon, Nina Afsar, Mehdi Nouraie, Julia C. Finkel, and Zenaide M.N. Quezado
Iron restriction in sickle cell anemia: Time for controlled clinical studies, Oswaldo Castro and Gregory J. Kato
Case studies evaluating transdermal continuous oxygen for the treatment of chronic sickle cell ulcers, Ikechukwu Igwegbe, Gladys Onojobi, Margaret O. Fadojutimi-Akinsiku, Alan M. Hirsh, Nanjin J. Park, Min Yao, and Vickie R. Driver
Therapeutics for postexposure treatment of Ebola virus infection, Marina Jerebtsova and Sergei Nekhai
Multicenter COMPACT study of COMplications in Patients with sickle cell disease and utilization of iron Chelation Therapy, Lanetta Jordan, Patricia Adams-Graves, Julie Kanter-Washko, Patricia A. Oneal, Medha Sasane, Francis Vekeman, Christine Bieri, Matthew Magestro, Andrea Marcellari, and Mei Sheng Duh
Rapamycin increases fetal hemoglobin and ameliorates the nociception phenotype in sickle cell mice, Alfia Khaibullina, Luis E.F. Almeida, Li Wang, Sayuri Kamimura, Edward C.C. Wong, Mehdi Nouraie, Irina Maric, Sarah Albani, Julia Finkel, and Zenaide M.N. Quezado
Inhibition of HIV-1 by curcumin A, a novel curcumin analog, Namita Kumari, Amol A. Kulkarni, Xionghao Lin, Charlee McLean, Tatiana Ammosova, Andrey Ivanov, Maria Hipolito, Sergei Nekhai, and Evaristus Nwulia
Blood transfusion and 30-day readmission rate in adult patients hospitalized with sickle cell disease crisis, Mehdi Nouraie and Victor R. Gordeuk
Complications in children and adolescents with Chuvash polycythemia, Adelina I. Sergueeva, Galina Y. Miasnikova, Lydia A. Polyakova, Mehdi Nouraie, Josef T. Prchal, and Victor R. Gordeuk
Activation of HIV-1 with nanoparticle-packaged small-molecule protein phosphatase-1-targeting compound, Kahli A. Smith, Xionghao Lin, Oleg Bolshakov, James Griffin, Xiaomei Niu, Dmytro Kovalskyy, Andrey Ivanov, Marina Jerebtsova, Robert E. Taylor, Emmanuel Akala, and Sergei Nekhai
Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1, Mudit Tyagi, Sergey Iordanskiy, Tatyana Ammosova, Namita Kumari, Kahli Smith, Denitra Breuer, Andrey V. Ilatovskiy, Yasemin Saygideğer Kont, Andrey Ivanov, Aykut Üren, Dmytro Kovalskyy, Michael Petukhov, Fatah Kashanchi, and Sergei Nekhai
Iron, inflammation, and early death in adults with sickle cell disease, Eduard J. Van Beers, Yanqin Yang, Nalini Raghavachari, Xin Tian, Darlene T. Allen, James S. Nichols, Laurel Mendelsohn, Sergei Nekhai, Victor R. Gordeuk, James G. Taylor, and Gregory J. Kato
Modulation of social deficits and repetitive behaviors in a mouse model of autism: The role of the nicotinic cholinergic system, Li Wang, Luis E.F. Almeida, Nicholas A. Spornick, Nicholas Kenyon, Sayuri Kamimura, Alfia Khaibullina, Mehdi Nouraie, and Zenaide M.N. Quezado
Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease, Xu Zhang, Wei Zhang, Santosh L. Saraf, Mehdi Nouraie, Jin Han, Michel Gowhari, Johara Hassan, Galina Miasnikova, Adelina Sergueeva, Sergei Nekhai, Rick Kittles, Roberto F. Machado, Joe G.N. Garcia, Mark T. Gladwin, Martin H. Steinberg, Paola Sebastiani, Donald A. McClain, and Victor R. Gordeuk
Submissions from 2014
1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription, Tatyana Ammosova, Maxim Platonov, Andrei Ivanov, Yasemin Saygideʇer Kont, Namita Kumari, Kylene Kehn-Hall, Marina Jerebtsova, Amol A. Kulkarni, Aykut Üren, Dmytro Kovalskyy, and Sergei Nekhai
Abnormal pulmonary function and associated risk factors in children and adolescents with sickle cell anemia, Manuel Arteta, Andrew Campbell, Mehdi Nouraie, Sohail Rana, Onyinye C. Onyekwere, Gregory Ensing, Craig Sable, Niti Dham, Deepika Darbari, Lori Luchtman-Jones, Gregory J. Kato, Mark T. Gladwin, Oswaldo L. Castro, Caterina P. Minniti, and Victor R. Gordeuk
Gastric Helicobacter pylori infection associates with an increased risk of colorectal polyps in African Americans, Hassan Brim, Marwah Zahaf, Adeyinka O. Laiyemo, Mehdi Nouraie, Guillermo I. Pérez-Pérez, Duane T. Smoot, Edward Lee, Hadie Razjouyan, and Hassan Ashktorab
Hydroxycarbamide treatment in sickle cell disease: Estimates of possible leukaemia risk and of hospitalization survival benefit, Oswaldo Castro, Mehdi Nouraie, and Patricia Oneal
Alpha-thalassaemia and response to hydroxyurea in sickle cell anaemia, Deepika S. Darbari, Mehdi Nouraie, James G. Taylor, Carlo Brugnara, Oswaldo Castro, and Samir K. Ballas
Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription, Philipp A. Ilinykh, Bersabeh Tigabu, Andrey Ivanov, Tatiana Ammosova, Yuri Obukhov, Tania Garron, Namita Kumari, Dmytro Kovalskyy, Maxim O. Platonov, Vasiliy S. Naumchik, Alexander N. Freiberg, Sergei Nekhai, and Alexander Bukreyev
Phenyl-1-Pyridin-2yl-Ethanone-Based Iron Chelators Increase IκB-α Expression, modulate CDK2 and CDK9 activities, and inhibit HIV-1 transcription, Namita Kumari, Sergey Iordanskiy, Dmytro Kovalskyy, Denitra Breuer, Xiaomei Niu, Xionghao Lin, Min Xu, Konstantin Gavrilenko, Fatah Kashanchi, Subhash Dhawan, and Sergei Nekhai
Prediction of fetal hemoglobin in sickle cell anemia using an ensemble of genetic risk prediction models, Jacqueline N. Milton, Victor R. Gordeuk, James G. Taylor, Mark T. Gladwin, Martin H. Steinberg, and Paola Sebastiani
Regulation of CDK9 activity by phosphorylation and dephosphorylation, Sergei Nekhai, Michael Petukhov, and Denitra Breuer
Sickle erythrocytes and platelets augment lung leukotriene synthesis with downregulation of anti-inflammatory proteins: Relevance in the pathology of the acute chest syndrome, Michael Opene, Joseph Kurantsin-Mills, Sumair Husain, and Basil O. Ibe
Differences in the clinical and genotypic presentation of sickle cell disease around the world, Santosh L. Saraf, Robert E. Molokie, Mehdi Nouraie, Craig A. Sable, Lori Luchtman-Jones, Gregory J. Ensing, Andrew D. Campbell, Sohail R. Rana, Xiao M. Niu, Roberto F. Machado, Mark T. Gladwin, and Victor R. Gordeuk
Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing, Xu Zhang, Wei Zhang, Shwu Fan Ma, Galina Miasniakova, Adelina Sergueeva, Tatiana Ammosova, Min Xu, Sergei Nekhai, Mehdi Nourai, Michael S. Wade, Josef T. Prchal, Joe G.N. Garcia, Roberto F. Machado, and Victor R. Gordeuk
Submissions from 2013
Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: A role for HIF in glucose metabolism, Donald A. McClain, Khadega A. Abuelgasim, Mehdi Nouraie, Juan Salomon-Andonie, Xiaomei Niu, Galina Miasnikova, Lydia A. Polyakova, Adelina Sergueeva, Daniel J. Okhotin, Daniel J. Okhotin, Rabia Cherqaoui, James E. Cox, Sabina Swierczek, Jihyun Song, M. Celeste Simon, Jingyu Huang, Judith A. Simcox, Donghoon Yoon, Josef T. Prchal, and Victor R. Gordeuk
Genetic determinants of haemolysis in sickle cell anaemia, Jacqueline N. Milton, Helen Rooks, Emma Drasar, Elizabeth L. McCabe, Clinton T. Baldwin, Efi Melista, Victor R. Gordeuk, Mehdi Nouraie, Gregory R. Kato, Caterina Minniti, James Taylor, Andrew Campbell, Lori Luchtman-Jones, Sohail Rana, Oswaldo Castro, Yingze Zhang, Swee Lay Thein, Paola Sebastiani, Mark T. Gladwin, D. B. Badesch, R. J. Barst, O. L. Castro, J. S.R. Gibbs, R. E. Girgis, J. C. Goldsmith, K. L. Hassell, G. J. Kato, L. Krishnamurti, S. Lanzkron, J. A. Little, R. F. Machado, C. R. Morris, O. Onyekwere, and E. B. Rosenzweig
Role of cellular iron and oxygen in the regulation of HIV-1 infection, Sergei Nekhai, Namita Kumari, and Subhash Dhawan
Reduced sensitivity of the ferroportin Q248H mutant to physiological concentrations of hepcidin, Sergei Nekhai, Min Xu, Altreisha Foster, Ishmael Kasvosve, Sharmin Diaz, Roberto F. Machado, Oswaldo L. Castro, Gregory J. Kato, James G. Taylor VI, and Victor R. Gordeuk
Asynchronous web-based learning, a practical method to enhance teaching in emergency medicine, Ali Pourmand, Raymond Lucas, and Mehdi Nouraie
Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood., Juan Salomon-Andonie, Galina Miasnikova, Adelina Sergueeva, Lydia A. Polyakova, Xiaomei Niu, Sergei Nekhai, and Victor R. Gordeuk
The phenotype of polycythemia due to Croatian homozygous VHL (571C>G:H191D) mutation is different from that of Chuvash polycythemia (VHL 598C>T:R200W), Nikica Ljubas Tomasic, Lucie Piterkova, Chad Huff, Ernest Bilic, Donghoon Yoon, Galina Y. Miasnikova, Adelina I. Sergueeva, Xiaomei Niu, Sergei Nekhai, Victor Gordeuk, and Josef T. Prchal
Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription, Rachel Van Duyne, Irene Guendel, Elizabeth Jaworski, Gavin Sampey, Zachary Klase, Hao Chen, Chen Zeng, Dmytro Kovalskyy, Mahmoud H. El Kouni, Benjamin Lepene, Alexis Patanarut, Sergei Nekhai, David H. Price, and Fatah Kashanchi
Heme oxygenase-1-mediated host cell response inhibits the susceptibility of prostate cancer cells to retroviral infection and retards their proliferation, Zhao Hua Zhou, Namita Kumari, Jennifer Catalano, Sergei Nekhai, Jasen Wise, Kenneth M. Yamada, and Subhash Dhawan
Heme oxygenase-1 induction alters chemokine regulation and ameliorates human immunodeficiency virus-type-1 infection in lipopolysaccharide-stimulated macrophages, Zhao Hua Zhou, Namita Kumari, Sergei Nekhai, Kathleen A. Clouse, Larry M. Wahl, Kenneth M. Yamada, and Subhash Dhawan
Submissions from 2012
Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1, Tatiana Ammosova, Maxim Platonov, Venkat R.K. Yedavalli, Yuri Obukhov, Victor R. Gordeuk, Kuan Teh Jeang, Dmytro Kovalskyy, and Sergei Nekhai
Helicobacter pylori protection against reflux esophagitis, Hassan Ashktorab, Omid Entezari, Mehdi Nouraie, Ehsan Dowlati, Wayne Frederick, Alfreda Woods, Edward Lee, Hassan Brim, Duane T. Smoot, Firoozeh Ghadyari, Farin Kamangar, and Hadie Razjouyan
CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90, Denitra Breuer, Alexander Kotelkin, Tatiana Ammosova, Namita Kumari, Andrey Ivanov, Andrey V. Ilatovskiy, Monique Beullens, Philip R. Roane, Mathieu Bollen, Michael G. Petukhov, Fatah Kashanchi, and Sergei Nekhai
Markers of severe vaso-occlusive painful episode frequency in children and adolescents with sickle cell anemia, Deepika S. Darbari, Onyinye Onyekwere, Mehdi Nouraie, Caterina P. Minniti, Lori Luchtman-Jones, Sohail Rana, Craig Sable, Gregory Ensing, Niti Dham, Andrew Campbell, Manuel Arteta, Mark T. Gladwin, Oswaldo Castro, James G. Taylor VI, Gregory J. Kato, and Victor Gordeuk
Development of a sensitive HPLC method to measure in vitro permeability of E- and Z-isomeric forms of thiosemicarbazones in Caco-2 monolayers, Zufan Debebe, Sergei Nekhai, Meseret Ashenafi, David B. Lovejoy, Danuta S. Kalinowski, Victor R. Gordeuk, W. Malcolm Byrnes, Des R. Richardson, and Pradeep K. Karla
Dietary iron intake and serum ferritin concentration in 213 patients homozygous for the HFEC282Y hemochromatosis mutation, Victor R. Gordeuk, Laura Lovato, James C. Barton, Mara Vitolins, Gordon McLaren, Ronald T. Acton, Christine McLaren, Emily L. Harris, Mark Speechley, John H. Eckfeldt, Sharmin Diaz, Phyliss Sholinsky, and Paul Adams
Adenoviral E4 gene stimulates secretion of pigmental epithelium derived factor (PEDF) that maintains long-term survival of human glomerulus-derived endothelial cells, Marina Jerebtsova, Namita Kumari, Yuri Obuhkov, and Sergei Nekhai
HIV-1 resistant CDK2-knockdown macrophage-like cells generated from 293T cell-derived human induced pluripotent stem cells, Marina Jerebtsova, Namita Kumari, Min Xu, Gustavo Brito Alvim de Melo, Xiaomei Niu, Kuan Teh Jeang, and Sergei Nekhai
Sampling error in histopathology findings of nonalcoholic fatty liver disease: A post mortem liver histology study, Shahin Merat, Rasoul Sotoudehmanesh, Mehdi Nouraie, Masoumeh Peikan-Heirati, Sadaf G. Sepanlou, Reza Malekzadeh, and Masoud Sotoudeh
Use of ATP analogs to inhibit HIV-1 transcription, Aarthi Narayanan, Gavin Sampey, Rachel Van Duyne, Irene Guendel, Kylene Kehn-Hall, Jessica Roman, Robert Currer, Hervé Galons, Nassima Oumata, Benoît Joseph, Laurent Meijer, Massimo Caputi, Sergei Nekhai, and Fatah Kashanchi
Iron metabolism in cancer and infection, Sergei Nekhai and Victor R. Gordeuk
Sickle cell disease is associated with decreased HIV but higher HBV and HCV comorbidities in US hospital discharge records: A cross-sectional study, Mehdi Nouraie, Sergei Nekhai, and Victor R. Gordeuk
Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates, Enrico M. Novelli, Gregory J. Kato, Margaret V. Ragni, Yingze Zhang, Mariana E. Hildesheim, Mehdi Nouraie, Suchitra Barge, Michael P. Meyer, Andrea Cortese Hassett, Victor R. Gordeuk, Mark T. Gladwin, and Jeffrey S. Isenberg
Virus-producing cells determine the host protein profiles of HIV-1 virion cores, Steven Santos, Yuri Obukhov, Sergei Nekhai, Michael Bukrinsky, and Sergey Iordanskiy
Is opium a real risk factor for esophageal cancer or just a methodological artifact? hospital and neighborhood controls in case-control studies, Ramin Shakeri, Farin Kamangar, Dariush Nasrollahzadeh, Mehdi Nouraie, Hooman Khademi, Arash Etemadi, Farhad Islami, Hajiamin Marjani, Saman Fahimi, Alireza Sepehr, Atieh Rahmati, Christian C. Abnet, Sanford M. Dawsey, Paul Brennan, Paolo Boffetta, Reza Malekzadeh, and Reza Majdzadeh
Refining the value of secretory phospholipase A 2 as a predictor of acute chest syndrome in sickle cell disease: Results of a feasibility study (PROACTIVE), Lori Styles, Carrie G. Wager, Richard J. Labotka, Kim Smith-Whitley, Alexis A. Thompson, Peter A. Lane, Lillian E.C. McMahon, Robin Miller, Susan D. Roseff, Rathi V. Iyer, Lewis L. Hsu, Oswaldo L. Castro, Kenneth I. Ataga, Onyinye Onyekwere, Maureen Okam, Rita Bellevue, and Scott T. Miller
A Plasmodium-encoded cytokine suppresses T-cell immunity during malaria, Tiffany Sun, Thomas Holowka, Yan Song, Swen Zierow, Lin Leng, Yibang Chen, Huabao Xiong, Jason Griffith, Mehdi Nouraie, Philip E. Thuma, Elias Lolis, Chris J. Janse, Victor R. Gordeuk, Kevin Augustijn, and Richard Bucala
Submissions from 2011
Protein phosphatase-1 activates CDK9 by dephosphorylating ser175, Tatiana Ammosova, Yuri Obukhov, Alexander Kotelkin, Denitra Breuer, Monique Beullens, Victor R. Gordeuk, Mathieu Bollen, and Sergei Nekhai
Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription, Tatiana Ammosova, Venkat R.K. Yedavalli, Xiaomei Niu, Marina Jerebtsova, Aleyde Van Eynde, Monique Beullens, Mathieu Bollen, Kuan Teh Jeang, and Sergei Nekhai
Case-control study of vitamin D, dickkopf homolog 1 (DKK1) gene methylation, VDR gene polymorphism and the risk of colon adenoma in African Americans, Hassan Ashktorab, Bijou Nguza, Mehrnaz Fatemi, Mehdi Nouraie, Duane T. Smoot, Alejandro A. Schäffer, Sonia S. Kupfer, Carlos A. Camargo, and Hassan Brim
Esophageal carcinoma in African Americans: A five-decade experience, Hassan Ashktorab, Zahra Nouri, Mehdi Nouraie, Hadi Razjouyan, Edward E. Lee, Ehsan Dowlati, El Waleed El-Seyed, Adeyinka Laiyemo, Hassan Brim, and Duane T. Smoot
Senicapoc trial results support the existence of different sub-phenotypes of sickle cell disease with possible drug-induced phenotypic shifts, Oswaldo L. Castro, Victor R. Gordeuk, Mark T. Gladwin, and Martin H. Steinberg
