What causes hidradenitis suppurativa ?—15 years after

Authors

Christos C. Zouboulis, European Hidradenitis Suppurativa Foundation e.V.
Farida Benhadou, European Hidradenitis Suppurativa Foundation e.V.
Angel S. Byrd, Howard University College of Medicine
Nisha S. Chandran, European Hidradenitis Suppurativa Foundation e.V.
Evangelos J. Giamarellos-Bourboulis, European Hidradenitis Suppurativa Foundation e.V.
Gabriella Fabbrocini, European Hidradenitis Suppurativa Foundation e.V.
John W. Frew, Rockefeller University
Hideki Fujita, Nihon University School of Medicine
Marcos A. González-López, European Hidradenitis Suppurativa Foundation e.V.
Philippe Guillem, European Hidradenitis Suppurativa Foundation e.V.
Wayne P.F. Gulliver, European Hidradenitis Suppurativa Foundation e.V.
Iltefat Hamzavi, Wayne State University
Yildiz Hayran, Ankara Numune Education and Research Hospital
Barbara Hórvath, European Hidradenitis Suppurativa Foundation e.V.
Sophie Hüe, Inserm
Robert E. Hunger, European Hidradenitis Suppurativa Foundation e.V.
John R. Ingram, European Hidradenitis Suppurativa Foundation e.V.
Gregor B.E. Jemec, European Hidradenitis Suppurativa Foundation e.V.
Qiang Ju, European Hidradenitis Suppurativa Foundation e.V.
Alexa B. Kimball, Harvard Medical School
Joslyn S. Kirby, Penn State Health Milton S. Hershey Medical Center
Maria P. Konstantinou, Universite Paul Sabatier Toulouse III
Michelle A. Lowes, Rockefeller University
Amanda S. MacLeod, Duke University
Antonio Martorell, European Hidradenitis Suppurativa Foundation e.V.
Angelo V. Marzano, European Hidradenitis Suppurativa Foundation e.V.
Łukasz Matusiak, European Hidradenitis Suppurativa Foundation e.V.
Aude Nassif, European Hidradenitis Suppurativa Foundation e.V.
Elena Nikiphorou, King's College Hospital
Georgios Nikolakis, European Hidradenitis Suppurativa Foundation e.V.
André Nogueira da Costa, European Hidradenitis Suppurativa Foundation e.V.
Martin M. Okun, Fort HealthCare
Lauren A.V. Orenstein, Emory University School of Medicine
José Carlos Pascual, European Hidradenitis Suppurativa Foundation e.V.

Document Type

Article

Publication Date

12-1-2020

Abstract

The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International Hidradenitis Suppurativa Research Symposium held March 30–April 2, 2006 in Dessau, Germany with 33 participants were prophetic when they wrote “Hopefully, this heralds a welcome new tradition: to get to the molecular heart of HS pathogenesis, which can only be achieved by a renaissance of solid basic HS research, as the key to developing more effective HS therapy.” (Kurzen et al. What causes hidradenitis suppurativa? Exp Dermatol 2008;17:455). Fifteen years later, there is no doubt that the desired renaissance of solid basic HS research is progressing with rapid steps and that HS has developed deep roots among inflammatory diseases in Dermatology and beyond, recognized as “the only inflammatory skin disease than can be healed”. This anniversary article of 43 research-performing authors from all around the globe in the official journal of the European Hidradenitis Suppurativa Foundation e.V. (EHSF e.V.) and the Hidradenitis Suppurativa Foundation, Inc (HSF USA) summarizes the evidence of the intense HS clinical and experimental research during the last 15 years in all aspects of the disease and provides information of the developments to come in the near future.

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