Document Type


Publication Date

January 2015


Antiretroviral medication adherence behaviour among Thai youth with perinatal HIV in Thailand has received growingattention. However, few studies have examined individual predictors of antiretroviral adherence using multipleself-reports. A convenience sample of 89 Thai youth (interquartile range 14–16 years) with perinatal HIV at threepaediatric programmes in Chiang Mai completed a structured questionnaire and reported their antiretroviral adherencein the past one, seven and 30 days using count-based recall and a visual analog scale. Mean self-reported adherencerates ranged from 83.5% (past 30 days) to 99.8% (yesterday) of the time. One-inflated beta regression models were usedto examine the associations between antiretroviral adherence outcomes, treatment self-efficacy, depression, anxiety,social support and beliefs/attitudes about medications. Higher percentage of medications taken in the past 30 dayswas independently associated with higher treatment self-efficacy and fewer symptoms of depression. Adherencemonitoring would benefit from focal assessment of youth depression and perceived capacity to follow their antiretroviralregimen.