Regulation of rat liver phosphofructokinase levels in Morris hepatomas

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The levels of the major liver phosphofructokinase isozyme (PFK-L2) and the PFK regulatory factor were measured in adult and fetal liver as well as Morris hepatomas of different differentiation states. The results indicate that both the PFK-L2 activity and the PFK regulatory factor levels in well and highly differentiated hepatomas are not statistically different from the amounts found in adult liver. In the poorly differentiated hepatomas and fetal liver, the levels of both PFK-L2 and PFK regulatory factor are approximately 2 and 3 fold greater, respectively, than what was found in adult liver. © 1979.

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