Affluence does not influence breast cancer outcomes in African American women
The aim of this study was to determine the impact of race and socioeconomic status on breast tumor clinicopathological features and survival outcomes. This study used breast cancer data from the Washington D.C. Cancer Registry (2000–2010). Logistic regression and survival analysis assessed the association between race, socioeconomic (SES) variables, clinicopathological variables, recurrence-free survival and overall survival. African American (AA) breast cancer patients had an increased risk for stage III, ER-, and PR- breast cancer compared with White and Hispanic breast cancer patients. Additionally, D.C. geographical areas of lower socioeconomic status had higher incidences of stage III and stage IV breast cancer. A nested analysis demonstrated that AAs with higher median incomes compared with AAs with lower incomes revealed no differences for clinicopathological variables, nor were differences found between overall and recurrence-free survival. This study suggests that the biology of breast cancer in AAs could be driving breast cancer disparities.
Ricks-Santi, Luisel J.; Barley, Brittany; Winchester, Danyelle; Sultan, Dawood; McDonald, John; Kanaan, Yasmine; Pearson-Fields, Amari; Sutton, Arnethea L.; Sheppard, Vanessa; and Williams, Carla, "Affluence does not influence breast cancer outcomes in African American women" (2018). Howard University Cancer Center Faculty Publications. 23.