Legume intake and reduced colorectal adenoma risk in African-Americans.
Colorectal adenomas are known precursors for colorectal cancer. Several studies have shown that dietary factors can influence adenoma formation and growth. This study was conducted using African-American men and women who were undergoing colonoscopies in order to examine the relationship between selected dietary factors and the risk for colon polyps. In a case-control design, 186 men and women with a mean of 58 years of age were studied. A multiple logistic regression model was used to adjust for potential confounding variables and to determine which factors influence colorectal adenoma risk. Study results revealed that consumption of legumes such as dried beans, split peas, or lentils was negatively associated with risk (OR = 0.19; 95% CI: 0.04-0.91). Legumes are a good source of dietary fiber and of phytochemical compounds that may play a role in reducing adenoma formation or growth, thereby decreasing the risk of colorectal cancer. Nurses working with African-Americans should encourage consumption of these foods to decrease this risk.
Agurs-Collins, Tanya; Smoot, Duane; Afful, Joseph; Makambi, Kepher; and Adams-Campbell, Lucile L., "Legume intake and reduced colorectal adenoma risk in African-Americans." (2006). Howard University Cancer Center Faculty Publications. 103.